4 edition of Biological action of metal ions found in the catalog.
Biological action of metal ions
Includes bibliographical references and indexes.
|Statement||edited by Helmut Sigel.|
|Series||Metal ions in biological systems ; v. 6|
|LC Classifications||QP531 .S53 vol. 6, QP535.Z6 .S53 vol. 6|
|The Physical Object|
|Pagination||xiii, 453 p. :|
|Number of Pages||453|
|LC Control Number||76017336|
Skip to main content. This volume is devoted to the research area regarding the biological properties of metal alkyl derivatives, offering an authoritative account of this subject by 16 scientists. In 11 chapters, Biological Properties of Metal Alkyl Derivatives highlights, in detail, derivatives of germanium, tin, Price: $ The Alkali Metal Ions: Their Role for Life - Ebook written by Astrid Sigel, Helmut Sigel, Roland K. O. Sigel. Read this book using Google Play Books app on your PC, android, iOS devices. Download for offline reading, highlight, bookmark or take notes while you read The Alkali Metal Ions: Their Role for 5/5(2). and Zn2+), in aqueous solution, and their suitability for metal speciation and biological/biochemical studies involving the metal ions. The research was done in order to quantify the overall stability constants of metal ions and these pH buffers by two independent techniques, at a constant ionic strength (potassium nitrate M) and ºC.
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The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry.
Metallothionins are proteins rich in metal ions found in living systems. The divalent cations Zn 2+, Ca 2+ and Mg 2+ prevent cytotoxicity and in vivo antagonize Cd-induced carcinogenesis.
Lack of body iron is common in cancer patients and it is associated with complications in surgery and in animal by: For instance, ions such as Fe 2+ can bind to the hemoglobin and myoglobin protein to help transport oxygen to organs in the body.
Other metals like magnesium and copper act to stabilize the shapes of enzymes. However, there are some metal ions that are highly toxic in excessive amounts.
The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry.
Buy Metal Ions in Biological Systems: Biological Action of Metal Ions (Metal ions in biological systems ; v. 6) on FREE SHIPPING on qualified orders.
ions suitable for forming ternary complexes with enzymes which re-quire a crosslinking cation in order to produce a desired geometry between the protein and the substrate before the reaction can pro-ceed.
In summary, Mg performs biological functions under circumstances where there is a need for a small, strongly electropositive, mobile,File Size: KB.
Evolution of metal ions in biological systems refers to the incorporation of metallic ions into living organisms and how it has changed over time.
Metal ions have been associated with biological systems for billions of years, but only in the last century have scientists began. Metal ions play key roles in biology.
Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological book is structured around the periodic table and focuses on the control of metal ions in cells.
It addresses the molecular aspects of binding, transport. Interaction of Metal Ions with Streptonigrin and Biological Properties of the Complexes 4. Bleomycin Antibiotics: Metal Complexes and Their Biological Action 5.
Interaction between Valinomycin and Metal Ions 6. Beauvericin and the Other Enniatins 7. Complexing Properties of Gramicidins 8. Nactins: Their Complexes and Biological Properties 9. Book series. I have just come across this article. Editors appear to be unaware of the extensive series of books with the collective title of Metal ions in Life Sciences.
The latest volume (18) is Metallo-Drugs: Development and Action of Anticancer Agents. Publisher's information at De Gruyter, publisher. Metal ions play key roles in biology.
Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in : Hardcover.
It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs.
Metal ions in biological catalysis: From enzyme databases to general principles Article (PDF Available) in JBIC Journal of Biological Inorganic Chemistry 13(8) August with 4, Reads.
MILS provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes).
Some such metal ions are K+, Cu+, Fe2+, Mg2+, Mn2+, Ca2+, Cu2+, Zn2+, Fe3+ etc, Common metal ions which play a function in enzyme action are mentioned below: – 1. Magnesium ions help the enzymes that catalyze the synthesis of oligosaccharides and proteins. METAL IONS IN BIOLOGY Occur in several forms Most advanced class- Metalloenzymes or BIOLOGICAL CATALYSTS Specific role Major- d-block elements But s-block elements are also important – -Structural role (Ca) -Enzymatic action(Mg) -Homeostatic balance (Na & K).
The overall picture emerging from the overview of Metal-MACiE is that redox-inert metal ions are used in enzymes to stabilize negative charges and to activate substrates by virtue of their Lewis acid properties, whereas redox-active metal ions can be used both as Lewis acids and as redox by: Biological Aspects of Metal Enolates.
In book: PATAI'S Chemistry of Functional Groups, pp is a well-known tryptophan metabolite involved in many biological processes. Metal ions. Several heavy metals are found naturally in the earth crust and are exploited for various industrial and economic purposes. Among these heavy metals, a few have direct or indirect impact on the human body.
Some of these heavy metals such as copper, cobalt, iron, nickel, magnesium, molybdenum, chromium, selenium, manganese and zinc have functional roles which are essential for various diverse Cited by: 6. Because metal ions are positively charged ions that are stable in multiple oxidation states and can form strong yet conformationally changeable bonds, they become attractive catalytic substances.
Many biochemical reactions depend on the presence of metal ions, which are a part of coordination complexes. Find many great new & used options and get the best deals for Metal Ions in Biological Systems: Biological Actions of Metal Ions at the best online prices at eBay.
Free shipping for many products. Metal Ions in Biological Systems by Helmut Sigel,available at Book Depository with free delivery : Helmut Sigel. Metal Ions in Biological Systems: Volume Antibiotics and Their Complexes - CRC Press Book This volume is an attempt to improve the understanding of the coordination chemistry and action of the biologically important compounds, also termed antibiotics, and to stimulate further research in this area, describing the properties of the.
Page - Metal Ions in Biological Systems, vol. 23, Nickel and Its Role in Biology. Appears in 12 books from Page xv - University of Mississippi Medical. Metal Ions in Biological Systems: Volume 9: Amino Acids and Derivatives as Ambivalent Ligands 1st Edition.
Helmut Sigel J This book focuses on the connection between the chemistry of metal ions and their role for life, and covers complexes with a number of. Platinum and Biological Systems Metal Ions in Biological Systems, Volume Interactions of Metal Ions with Nucleotides.
Nucleic Acid, and Their Constituents EDITED BY ASTRID SIGEL AND HELMUT SIGEL, Marcel Dekker, New York,pages, ISBNU.S Nucleotide- and nucleic acid-metal ion inter- actions have been a major focus of research for. Vol entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry.
The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the s is a landmark in metallodrug-based.
Offering an authoritative and timely account by twenty-nine internationally recognized experts, Metal Ions in Biological Systems: Metal Complexes in Tumor Diagnosis and as Anticancer Agents is devoted solely to the vital research area concerning metal complexes in Author: Helmut Sigel.
The water is the target of action of the metal which, upon binding of the proper substrate, abstracts a proton to create a nucleophilic hydroxyl group that attacks the peptide bond, cleaving it (Figure ).
Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes.
The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in fields like biochemistry, inorganic chemistry, coordination. Topics include toxic metals, metals used in biological systems and the overlap of these categories; issues associated with the uptake, transport and storage of metal ions; and the benefits gained by using metals in biological molecules.
The learning object includes a PowerPoint presentation (with various animations). This book describes drug metal-ion interactions in the gut and deals with the deficiency of zinc and iron and their pharmacological use.
It covers anti-inflammatory activities of copper and gold complexes and considers the role of metal ions and chelating agents in anti-viral chemotherapy. Read "Metal Ions in Biological Systems Volume Interrelations Between Free Radicals and Metal Ions in Life Processes" by available from Rakuten Kobo.
Continues the tradition of excellence established in previous volumes in this acclaimed series. Volume 36 focuses on the Brand: CRC Press. Some such metal ions are K+,Cu+,Fe2+,Mg2+,Mn2+,Ca2+,Cu2+,Zn2+,Fe3+ etc, Common metal ions which play a role in enzyme action are mentioned below: 1.
Magnesium ions help the enzymes that catalyze the synthesis of oligosaccharides and proteins. Alkali metal ions play very important roles in all biological systems, some of them are essential for life. Their concentration depends on several physiological factors and is very variable. For example, sodium concentrations in human fluids vary from quite low (e.g., mmol dm(-3) in mature mater.
The metal ions, nowthrough exposure to a proportional concentration of cop- freed from the complex, are able to react further in yetper ions .
another cycle for the formation of additional bisglutathi- one and further oxidation [24,25] The Sigels' Series. Metal Ions in Life Sciences. Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes.
It is an old experience that metals are indispensable for life. The series reflects the interdisciplinary nature of Biological Inorganic.
Metal ions play important roles in many biological systems. In particular, metal ions are required for the activity of a large number of enzymes and proteins. Metal ions are well suited for these functions because of the following properties: (1) Metal ions are almost always positively charged and, hence, electrophilic.
The book also considers catalysis by metal ions, metal complexes, and metalloenzymes before concluding with a chapter that examines the reactions of ligands in organometallic complexes.
This monograph is written for teachers, students, and practitioners of Book Edition: 1. Abstract:Heterocyclic compounds containing nitrogen ions, like pyrazoles, aziridines, diaziridines and their metal ion complexes with Cu(II), Zn(II) and Ru(III) and others exhibit a wide range of biological activity, including mainly anti-inflammatory, antioxidant, anticancer, and antimicrobial properties.
Biological significance of these Cited by: 2.Essential metal ions are tightly controlled in biological systems. An understanding of metal metabolism and homeostasis is being developed from quantitative information of the sizes, concentrations, and dynamics of cellular and subcellular metal ion pools.
In the case of human zinc metabolism, minimally 24 proteins of two zinc transporter Cited by: Intestinal Absorption of Metal Ions, Trace Elements, and Radionuclides focuses on the transport of metal ions across biological membranes. The selection first discusses fundamental considerations of ion transport across biological membranes, including passage of ions through the pores of gels or membranes; mobilities of organic and inorganic ions in water; and complexing of alkali metal Book Edition: 1.